MLL3 antibody (N-Term)

Catalog No. ABIN6242809

Product Details anti-MLL3 Antibody

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Binding Specificity: AA 1142-1175, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.

Clone: RB52487

Isotype: Ig Fraction

Application Details

Application Notes: IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MLL3

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Alternative Name: MLL3 (KMT2C Products)

Synonyms: HALR antibody, MLL3 antibody, E330008K23Rik antibody, Mll3 antibody, mKIAA1506 antibody, lysine methyltransferase 2C antibody, lysine (K)-specific methyltransferase 2C antibody, KMT2C antibody, Kmt2c antibody

Background: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Molecular Weight: 541370

UniProt: Q8NEZ4

Pathways: Warburg Effect