ANAPC11 antibody (AA 56-94)

Catalog No. ABIN6242773

Product Details anti-ANAPC11 Antibody

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Binding Specificity: AA 56-94

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC11 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANAPC11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 56-94 amino acids from human ANAPC11.

Clone: RB56253

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for ANAPC11

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Alternative Name: ANAPC11 (ANAPC11 Products)

Background: Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Molecular Weight: 9841

UniProt: Q9NYG5