Oligophrenin 1 antibody (AA 284-315)

Catalog No. ABIN6242734

Product Details anti-Oligophrenin 1 Antibody

Target: Oligophrenin 1 (OPHN1)

Binding Specificity: AA 284-315

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oligophrenin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This OPHN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the Central region of human OPHN1.

Clone: RB53386

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Oligophrenin 1

Target: Oligophrenin 1 (OPHN1)

Alternative Name: OPHN1 (OPHN1 Products)

Background: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).

Molecular Weight: 91641

UniProt: O60890