This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ICB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ICB1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Hartweger, Schweighoffer, Davidson, Peirce, Wack, Tybulewicz: "Themis2 is not required for B cell development, activation, and antibody responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 700-7, (2014) (PubMed).
Peirce, Brook, Morrice, Snelgrove, Begum, Lanfrancotti, Notley, Hussell, Cope, Wait: "Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production." in: PLoS ONE, Vol. 5, Issue 7, pp. e11465, (2010) (PubMed).
Target
C1orf38
(Chromosome 1 Open Reading Frame 38 (C1orf38))