SRY antibody (AA 81-112)

Catalog No. ABIN6242645

Product Details anti-SRY Antibody

Target: SRY (Sex Determining Region Y (SRY))

Binding Specificity: AA 81-112

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRY antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SRY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-112 amino acids from the Central region of human SRY.

Clone: RB53826

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SRY

Target: SRY (Sex Determining Region Y (SRY))

Alternative Name: SRY (SRY Products)

Synonyms: SRXX1 antibody, SRXY1 antibody, TDF antibody, TDY antibody, SRYGENE antibody, Sry1 antibody, Sry3BI antibody, Tdf antibody, Tdy antibody, SRY antibody, sex determining region Y antibody, sex determining region of Chr Y antibody, SRY antibody, Sry antibody

Background: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Molecular Weight: 23884

UniProt: Q05066