Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RAD9A antibody (N-Term)

RAD9A Reactivity: Mouse WB Host: Rabbit Polyclonal RB52362 unconjugated
Catalog No. ABIN6242554
  • Target See all RAD9A Antibodies
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Binding Specificity
    • 22
    • 15
    • 15
    • 15
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-62, N-Term
    Reactivity
    • 147
    • 47
    • 22
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 158
    • 9
    • 1
    Rabbit
    Clonality
    • 159
    • 9
    Polyclonal
    Conjugate
    • 69
    • 15
    • 13
    • 12
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAD9A antibody is un-conjugated
    Application
    • 136
    • 82
    • 54
    • 41
    • 40
    • 29
    • 12
    • 10
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This mouse Rad9a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 29-62 amino acids from the N-terminal region of mouse Rad9a.
    Clone
    RB52362
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RAD9A Primary Antibody
  • Application Notes
    WB: 1:2000. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Alternative Name
    Rad9a (RAD9A Products)
    Synonyms
    RAD9 antibody, Rad9 antibody, rad9a antibody, MGC89062 antibody, XRad9 antibody, rad9 antibody, RAD9 checkpoint clamp component A antibody, RAD9 checkpoint clamp component B antibody, RAD9 checkpoint clamp component A L homeolog antibody, RAD9A antibody, Rad9a antibody, rad9a antibody, rad9b antibody, rad9a.L antibody
    Background
    Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
    Molecular Weight
    42059
    UniProt
    Q9Z0F6
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
You are here:
Support