PRDM16 antibody (AA 771-804)

Catalog No. ABIN6242535

Product Details anti-PRDM16 Antibody

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Binding Specificity: AA 771-804

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM16 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRDM16 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 771-804 amino acids from the Central region of human PRDM16.

Clone: RB49517

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PRDM16

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Alternative Name: PRDM16 (PRDM16 Products)

Synonyms: PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody

Background: Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Molecular Weight: 140251

UniProt: Q9HAZ2

Pathways: Stem Cell Maintenance, Brown Fat Cell Differentiation