PFN1 antibody (C-Term)
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- Target See all PFN1 Antibodies
- PFN1 (Profilin 1 (PFN1))
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Binding Specificity
- AA 87-120, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PFN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.
- Clone
- RB49649
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PFN1 Primary Antibody
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- Application Notes
- WB: 1:8000. WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- PFN1 (Profilin 1 (PFN1))
- Alternative Name
- PFN1 (PFN1 Products)
- Synonyms
- GmPRO1 antibody, GmPRO2 antibody, PRO1 antibody, Profilin-1 antibody, profilin-1 antibody, profilin antibody, MGC130883 antibody, Profilin1 antibody, XProfilin1 antibody, sb:cb813 antibody, wu:fa91a03 antibody, ALS18 antibody, Pfn antibody, F6F22.21 antibody, F6F22_21 antibody, PFN1 antibody, PROFILIN 1 antibody, profilin 1 antibody, profilin antibody, profilin 1 antibody, profilin 1 L homeolog antibody, profilin homolog 1 antibody, Profilin-1 antibody, PRO2 antibody, PFN1 antibody, pfn1.L antibody, pfn1 antibody, Pfn1 antibody, PRF1 antibody, prf1 antibody, pfn-1 antibody
- Background
- Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
- Molecular Weight
- 15054
- UniProt
- P07737
- Pathways
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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