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PFN1 antibody (C-Term)

PFN1 Reactivity: Human WB Host: Rabbit Polyclonal RB49649 unconjugated
Catalog No. ABIN6242520
  • Target See all PFN1 Antibodies
    PFN1 (Profilin 1 (PFN1))
    Binding Specificity
    • 14
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 87-120, C-Term
    Reactivity
    • 54
    • 32
    • 30
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 62
    • 4
    Rabbit
    Clonality
    • 55
    • 11
    Polyclonal
    Conjugate
    • 22
    • 9
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    This PFN1 antibody is un-conjugated
    Application
    • 32
    • 24
    • 14
    • 13
    • 11
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.
    Clone
    RB49649
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PFN1 Primary Antibody
  • Application Notes
    WB: 1:8000. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    PFN1 (Profilin 1 (PFN1))
    Alternative Name
    PFN1 (PFN1 Products)
    Synonyms
    GmPRO1 antibody, GmPRO2 antibody, PRO1 antibody, Profilin-1 antibody, profilin-1 antibody, profilin antibody, MGC130883 antibody, Profilin1 antibody, XProfilin1 antibody, sb:cb813 antibody, wu:fa91a03 antibody, ALS18 antibody, Pfn antibody, F6F22.21 antibody, F6F22_21 antibody, PFN1 antibody, PROFILIN 1 antibody, profilin 1 antibody, profilin antibody, profilin 1 antibody, profilin 1 L homeolog antibody, profilin homolog 1 antibody, Profilin-1 antibody, PRO2 antibody, PFN1 antibody, pfn1.L antibody, pfn1 antibody, Pfn1 antibody, PRF1 antibody, prf1 antibody, pfn-1 antibody
    Background
    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
    Molecular Weight
    15054
    UniProt
    P07737
    Pathways
    Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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