MED15 antibody (C-Term)

Catalog No. ABIN6242465

Product Details anti-MED15 Antibody

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Binding Specificity: AA 712-746, C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This mouse Med15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of mouse Med15.

Clone: RB51171

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MED15

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Alternative Name: Med15 (MED15 Products)

Synonyms: Arc105 antibody, BcDNA:GH03922 antibody, CG4184 antibody, Dmel\\CG4184 antibody, Med15 antibody, Med9/ARC105 antibody, dARC105 antibody, med15 antibody, PCQAP antibody, MED15 antibody, DKFZp459O0325 antibody, ARC105 antibody, CAG7A antibody, CTG7A antibody, TIG-1 antibody, TIG1 antibody, TNRC7 antibody, A230074L19Rik antibody, AW536074 antibody, Pcqap antibody, arc105 antibody, fi85b10 antibody, pcqap antibody, wu:fd19g01 antibody, wu:fi19d01 antibody, wu:fi85b10 antibody, zgc:55839 antibody, Mediator complex subunit 15 antibody, mediator complex subunit 15 antibody, mediator of RNA polymerase II transcription subunit 15 antibody, mediator complex subunit 15 L homeolog antibody, MED15 antibody, LOC100195848 antibody, Med15 antibody, med15 antibody, med15.L antibody

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity).

Molecular Weight: 86607

UniProt: Q924H2

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha