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MBD2 antibody (AA 10-228)

MBD2 Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 1812CT625-9-45 unconjugated
Catalog No. ABIN6242434
  • Target See all MBD2 Antibodies
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Binding Specificity
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-228
    Reactivity
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 45
    • 1
    • 1
    Mouse
    Clonality
    • 45
    • 2
    Monoclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD2 antibody is un-conjugated
    Application
    • 40
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
    Clone
    1812CT625-9-45
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MBD2 Primary Antibody
  • Application Notes
    WB: 1:2000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Alternative Name
    MBD2 (MBD2 Products)
    Synonyms
    MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
    Background
    Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
    Molecular Weight
    43255
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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