Drosophila SUMO (N-Term) antibody

Catalog No. ABIN6242330

Product Details

Target: Drosophila SUMO

Binding Specificity: N-Term

Reactivity: Drosophila melanogaster, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Please inquire

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila SUMO1.

Clone: RB3486

Isotype: Ig Fraction

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References

Matsui, Sharma, Cooke, Wakimoto, Rasool, Hayworth, Hylton, Tomkiel: "Nuclear structure and chromosome segregation in Drosophila male meiosis depend on the ubiquitin ligase dTopors." in: Genetics, Vol. 189, Issue 3, pp. 779-93, (2012) (PubMed).

Target Details

Target: Drosophila SUMO

Background: Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.

Molecular Weight: 10124

UniProt: O97102