CD59 antibody (AA 74-110)

Catalog No. ABIN6242239

Product Details anti-CD59 Antibody

Target: CD59

Binding Specificity: AA 74-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD59 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD59 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 74-110 amino acids from the Central region of human CD59.

Clone: RB56691

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:2000. IHC-P-Leica: 1:1000. IHC: 1:250. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for CD59

Target: CD59

Alternative Name: CD59 (CD59 Products)

Background: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Molecular Weight: 14177

UniProt: P13987

Pathways: Complement System