NFE4 antibody (C-Term)

Catalog No. ABIN6242126

Product Details anti-NFE4 Antibody

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Binding Specificity: AA 135-169, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFE4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-169 amino acids from the C-terminal region of human NFE4.

Clone: RB51299

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for NFE4

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Alternative Name: NFE4 (NFE4 Products)

Synonyms: NF-E4 antibody, nuclear factor, erythroid 4 antibody, NFE4 antibody

Background: Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.

Molecular Weight: 19019

UniProt: Q86UQ8