PEG10 antibody

Catalog No. ABIN6241773

Product Details anti-PEG10 Antibody

Target: PEG10 (Paternally Expressed 10 (PEG10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PEG10 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Immunogen: Recombinant Protein

Application Details

Application Notes: IP: 1:500. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Target Details for PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Alternative Name: PEG10 (PEG10 Products)

Synonyms: EDR antibody, HB-1 antibody, MEF3L antibody, Mar2 antibody, Mart2 antibody, RGAG3 antibody, AA407948 antibody, Edr antibody, MyEF-3 antibody, paternally expressed 10 antibody, PEG10 antibody, Peg10 antibody

Background: Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).

UniProt: Q86TG7