WDR77 antibody

Catalog No. ABIN6241347

Product Details anti-WDR77 Antibody

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This WDR77 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Immunogen: Recombinant Protein

Application Details

Application Notes: WB: 1:1000. ICC: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Target Details for WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Alternative Name: WDR77 (WDR77 Products)

Synonyms: MEP-50 antibody, MEP50 antibody, Nbla10071 antibody, RP11-552M11.3 antibody, p44 antibody, p44/Mep50 antibody, 2610003I18Rik antibody, 2610312E17Rik antibody, C79984 antibody, p44/MEP50 antibody, RGD1310479 antibody, mep50 antibody, valois antibody, WDR77 antibody, zgc:65780 antibody, zgc:77274 antibody, WD repeat domain 77 antibody, WD repeat domain 77 S homeolog antibody, WDR77 antibody, Wdr77 antibody, wdr77.S antibody, wdr77 antibody

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization