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Cyclin H antibody

CCNH Reactivity: Human WB, IP Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6241261
  • Target See all Cyclin H (CCNH) Antibodies
    Cyclin H (CCNH)
    Reactivity
    • 82
    • 46
    • 27
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 70
    • 14
    Mouse
    Clonality
    • 64
    • 20
    Monoclonal
    Conjugate
    • 49
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    This Cyclin H antibody is un-conjugated
    Application
    • 53
    • 32
    • 20
    • 19
    • 15
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Immunogen
    Recombinant Protein
    Top Product
    Discover our top product CCNH Primary Antibody
  • Application Notes
    IP: 1:500. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    Cyclin H (CCNH)
    Alternative Name
    Cyclin H (CCNH Products)
    Background
    Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
    UniProt
    P51946
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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