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CRTC1 antibody

CRTC1 Reactivity: Human WB, IP, FACS, ICC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6241239
  • Target See all CRTC1 Antibodies
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Reactivity
    • 67
    • 37
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 12
    • 1
    Mouse
    Clonality
    • 56
    • 13
    Monoclonal
    Conjugate
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRTC1 antibody is un-conjugated
    Application
    • 52
    • 25
    • 20
    • 13
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Immunogen
    Recombinant Protein
    Top Product
    Discover our top product CRTC1 Primary Antibody
  • Application Notes
    IP: 1:500. WB: 1:1000. FC: 1:100. ICC: 1:300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Alternative Name
    MECT1 / Torc1 (CRTC1 Products)
    Synonyms
    MECT1 antibody, TORC-1 antibody, TORC1 antibody, WAMTP1 antibody, AI413414 antibody, Mect1 antibody, R74955 antibody, mKIAA0616 antibody, CRTC1 antibody, crtc1 antibody, fc68c05 antibody, pde4cb antibody, si:ch211-255d18.1 antibody, si:ch211-255d18.8 antibody, wu:fc68c05 antibody, CREB regulated transcription coactivator 1 antibody, CREB regulated transcription coactivator 1b antibody, CRTC1 antibody, Crtc1 antibody, crtc1 antibody, crtc1b antibody
    Background
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long- term potentiation (L-LTP) maintenance at the Schaffer collateral- CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
    UniProt
    Q6UUV9
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