GAB1 antibody (pTyr659)

Catalog No. ABIN6241063

Product Details anti-GAB1 Antibody

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Binding Specificity: pTyr659

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB1 antibody is un-conjugated

Application: Dot Blot (DB)

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Gab1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y659 of human Gab1.

Clone: RB10842

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for GAB1

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Alternative Name: Gab1 (GAB1 Products)

Synonyms: AA408973 antibody, AW107238 antibody, growth factor receptor bound protein 2-associated protein 1 antibody, GRB2-associated binding protein 1 antibody, GRB2 associated binding protein 1 antibody, Gab1 antibody, GAB1 antibody

Background: Gab1 is a member of the IRS1-like multisubstrate docking protein family. This protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis.

Molecular Weight: 76616

NCBI Accession: NP_002030, NP_997006

UniProt: Q13480

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals