PBK antibody (pThr9)
Quick Overview for PBK antibody (pThr9) (ABIN6241045)
Target
See all PBK AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 2-35, pThr9
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This Phospho-PBK/TOPK (Thr9) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-35 amino acids from the human Phospho-PBK/TOPK.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- WB: 1:4000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Expiry Date
- 6 months
-
-
- PBK (PDZ Binding Kinase (PBK))
-
Alternative Name
- PBK/TOPK
-
Background
- Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
-
Molecular Weight
- 36085
-
UniProt
- Q96KB5
Target
-