This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CLASP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T656 of human CLASP1.
CLASP1
Reactivity: Human
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
DB: 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Halim, Alvarez-Fernández, Xu, Aprelia, van den Toorn, Heck, Mohammed, Medema: "Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response." in: Science signaling, Vol. 6, Issue 272, pp. rs9, (2013) (PubMed).
Target
CLASP1
(Cytoplasmic Linker Associated Protein 1 (CLASP1))
CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170, MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle .