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H2AFX antibody (pSer139)

Name: H2AFX antibody (pSer139)
SKU: ABIN6241012
Price: 451 USD
Availability: InStock

H2AFX Reactivity: Human, Mouse WB, ICC Host: Mouse Monoclonal unconjugated

Western blot detection of Phosphorylation of H2A. (H2AFX antibody (pSer139))

Immunofluorescent analysis of Phosphorylation of H2A. (H2AFX antibody (pSer139))

ICC

2 images

Catalog No. ABIN6241012

Datasheet as PDF

Target See all H2AFX Antibodies

H2AFX (H2A Histone Family, Member X (H2AFX))
Binding Specificity
33

21

18

11

6

5

5

5

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer139
Reactivity
166

80

60

26

26

20

17

12

9

3

2

2

2

2

1
Human, Mouse
Host
148

18

2
Mouse
Compatible Secondaries
Clonality
122

46
Monoclonal
Conjugate
112

7

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1
This H2AFX antibody is un-conjugated
Application
132

48

43

38

35

27

23

20

16

11

8

4

4

3

2

2

2

1

1

1
Western Blotting (WB), Immunocytochemistry (ICC)

Immunogen

Recombinant Protein

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anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 938CT5-1-1 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reactivity: Human WB, ELISA, IF, ChIP Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibody
H2AFX Reactivity: Human WB, ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibody
H2AFX Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 980CT1-5-5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 8C5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibody
H2AFX Reactivity: Human WB, IF, ICC, ChIP Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (AA 12-141) antibody
H2AFX Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:2000. ICC: 1:400

Restrictions

For Research Use only
Format

Liquid

Storage

4 °C,-20 °C
Target

H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name

Histone H2A.X (H2AFX Products)

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.

UniProt

P16104

Pathways

Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus