Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

H2AFX antibody (pSer139)

H2AFX Reactivity: Human, Mouse WB, ICC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6241012
  • Target See all H2AFX Antibodies
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Binding Specificity
    • 32
    • 26
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139
    Reactivity
    • 167
    • 81
    • 60
    • 26
    • 26
    • 20
    • 17
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 148
    • 19
    • 2
    Mouse
    Clonality
    • 127
    • 42
    Monoclonal
    Conjugate
    • 108
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This H2AFX antibody is un-conjugated
    Application
    • 134
    • 51
    • 47
    • 37
    • 33
    • 27
    • 22
    • 19
    • 16
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    Immunogen
    Recombinant Protein
    Top Product
    Discover our top product H2AFX Primary Antibody
  • Application Notes
    WB: 1:2000. ICC: 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C,-20 °C
  • Target
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Alternative Name
    Histone H2A.X (H2AFX Products)
    Synonyms
    H2A.X antibody, H2A/X antibody, H2AX antibody, AW228881 antibody, H2ax antibody, Hist5-2ax antibody, gammaH2ax antibody, zgc:56329 antibody, h2a.x antibody, h2a/x antibody, h2ax antibody, RGD1566119 antibody, h2a antibody, h2afx antibody, H2A histone family member X antibody, H2A histone family, member X antibody, H2A histone family member X L homeolog antibody, histone cluster 1, H2ah antibody, histone cluster 2, H2ab S homeolog antibody, histone H2AX antibody, H2AFX antibody, H2afx antibody, h2afx antibody, h2afx.L antibody, HIST1H2AH antibody, hist2h2ab.S antibody, LOC100522201 antibody, LOC100720536 antibody
    Background
    Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.
    UniProt
    P16104
    Pathways
    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
You are here:
Support