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CD200 antibody

CD200 Reactivity: Human FACS, IHC (fro), IHC (p) Host: Mouse Monoclonal OX-104 unconjugated
Catalog No. ABIN6240832
  • Target See all CD200 Antibodies
    CD200
    Reactivity
    • 92
    • 21
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 58
    • 43
    • 12
    Mouse
    Clonality
    • 60
    • 51
    Monoclonal
    Conjugate
    • 39
    • 16
    • 13
    • 8
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD200 antibody is un-conjugated
    Application
    • 52
    • 50
    • 33
    • 25
    • 15
    • 14
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
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    • 1
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    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    recombinant human CD200
    Clone
    OX-104
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD200 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CD200
    Alternative Name
    CD200 (CD200 Products)
    Synonyms
    MOX1 antibody, MOX2 antibody, MRC antibody, OX-2 antibody, CD200 antibody, Cspmo2 antibody, MRCOX2 antibody, Mox2 antibody, DKFZp459C0716 antibody, OX2 antibody, CD200 molecule antibody, Cd200 molecule antibody, CD200 antigen antibody, CD200 antibody, Cd200 antibody
    Background
    CD200 Molecule,CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.,MRC, MOX, OX-2
    Gene ID
    4345
    UniProt
    P41217
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