CD39 antibody (APC)
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- Target See all CD39 (ENTPD1) Antibodies
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD39 antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Specificity
- The mouse monoclonal antibody TU66, also known as Tü66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Clone
- TU66
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product ENTPD1 Primary Antibody
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- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Comment
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The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
- Alternative Name
- CD39 (ENTPD1 Products)
- Synonyms
- ATPDase antibody, CD39 antibody, NTPDase-1 antibody, MGC80631 antibody, zgc:100819 antibody, entpd1 antibody, MGC79567 antibody, 2610206B08Rik antibody, AA408691 antibody, Cd39 antibody, ectonucleoside triphosphate diphosphohydrolase 1 antibody, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog antibody, ENTPD1 antibody, Entpd1 antibody, entpd1.L antibody, entpd1 antibody
- Background
- Ectonucleoside triphosphate diphosphohydrolase 1,CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.,ETDH1, LCAA, Ecto-ATPase 1, Ecto-apyrase, ENTPD1
- Gene ID
- 953
- UniProt
- P49961
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