TGF-beta antibody (Biotin)
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- Target See all TGF-beta (TGFb) Antibodies
- TGF-beta (TGFb)
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Hamster, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TGF-beta antibody is conjugated to Biotin
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Application
- Neutralization (Neut), Functional Studies (Func)
- Purpose
- Mouse Monoclonal anti-TGF-beta (1D11.16.8), Biotin Conjugate
- Characteristics
- This MAb recognizes TGF beta 1, 2 and 3. Three TGF? ?s have been identified in mammals. TGF? ?1, TGF? ?2 and TGF? ?3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF? ? requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF? ?3 protein has approximately 80 % identity to the mature region of both TGF? ?1 and TGF? ?2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGF? ?'s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Bovine TGF-beta2 protein
- Clone
- 1D11-16-8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TGFb Primary Antibody
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- Application Notes
- Cytokine neutralization or functional assay, order Ab without BSA/azideOptimal dilution for a specific application should be determined by user
- Comment
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Salivary gland carcinoma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- TGF-beta (TGFb)
- Alternative Name
- TGF-beta (TGFb Products)
- Synonyms
- CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor, beta 1 antibody, TGFB1 antibody, Tgfb1 antibody
- Background
- GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
- Molecular Weight
- ~13 kDa
- Gene ID
- 7040, 7042, 7043
- Pathways
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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