KRT1 antibody (CF®405S)

Catalog No. ABIN6162003

Product Details anti-KRT1 Antibody (CF®405S)

Target: KRT1 (Cytokeratin HMW (KRT1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT1 antibody is conjugated to CF®405S

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Coating (Coat)

Purpose: Mouse Monoclonal anti-Cytokeratin, HMW (KRTH/1076), CF405S Conjugate

Characteristics: This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human KRT76 protein

Clone: KRTH-1076

Isotype: IgG1 kappa

Application Details

Application Notes: Immunofluorescence 1-2 μg/mL

• Western blotting 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Predicted to show broad species reactivity

Comment:

Skin, Adenocarcinomas

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for KRT1

Target: KRT1 (Cytokeratin HMW (KRT1))

Alternative Name: Cytokeratin, HMW (KRT1 Products)

Synonyms: CK1 antibody, EHK antibody, EHK1 antibody, EPPK antibody, K1 antibody, KRT1A antibody, NEPPK antibody, keratin 1 antibody, KRT1 antibody

Background: KRT2B, KRT2P, HUMCYT2A, Keratin, Type II Cytoskeletal 2 Oral, K2P, K76, CK-2P, Keratin 2p, Keratin-76, Cytokeratin 2, Cytokeratin-2P, Type-II Keratin Kb9

Molecular Weight: 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8)

Gene ID: 51350, 654392

UniProt: Q01546