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Iba1 antibody (FITC)
IBA1
Reactivity: Human, Rat
IHC (p), FACS
Host: Mouse
Monoclonal
1022-5
FITC
Product Details anti-Iba1 Antibody (FITC)
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Target
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Iba1 (IBA1)
(Ionized Calcium-binding Adapter Molecule 1 (IBA1))
Reactivity
All reactivities for Iba1 antibodies
Human, Rat
Host
All hosts for Iba1 antibodies
Mouse
Clonality
All clonalities for Iba1 antibodies
Monoclonal
Conjugate
All conjugates for Iba1 antibodies
This Iba1 antibody is conjugated to FITC
Application
All applications for Iba1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Specificity
The antibody reacts with AIF-1.
Cross-Reactivity (Details)
Species reactivity (tested):Human (Activated Macrophages) and Rat.
Purification
Affinity Chromatography
Immunogen
Purified Human recombinant AIF-1. Epitope not further characterized.
Clone
1022-5
Isotype
IgG2b
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.4 mg/mL
Buffer
PBS, pH 7.2, 0.09 % Sodium Azide, 10 mg/mL BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. Do not freeze working dilutions.
Storage
4 °C/-20 °C
Storage Comment
Store the lyophilized antibody at 2-8 °C. Freeze stock solution and aliquots thereof at -20 °C.
Target Details for Iba1
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Target
Iba1 (IBA1)
(Ionized Calcium-binding Adapter Molecule 1 (IBA1))
Alternative Name
AIF1 (IBA1 Products )
Synonyms
AIF-1 antibody, IBA1 antibody, IRT-1 antibody, IRT1 antibody, AI607846 antibody, D17H6S50E antibody, G1 antibody, Iba1 antibody, Bart1 antibody, iba1 antibody, mrf-1 antibody, fa04b11 antibody, wu:fa04b11 antibody, AIF antibody, AIF1 antibody, aif1 antibody, allograft inflammatory factor 1 antibody, AIF1 antibody, Aif1 antibody, aif1 antibody
Background
Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.Synonyms: AIF-1, Allograft inflammatory factor 1, IBA1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1
Gene ID
199
NCBI Accession
NP_001614
UniProt
P55008
Pathways
Smooth Muscle Cell Migration
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