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Ephrin B2 antibody (pTyr316)
EFNB2
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Ephrin B2 Antibody
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Target
See all Ephrin B2 (EFNB2) Antibodies
Ephrin B2 (EFNB2)
Binding Specificity
All epitopes for Ephrin B2 antibodies
pTyr316
Reactivity
All reactivities for Ephrin B2 antibodies
Human, Mouse
Host
All hosts for Ephrin B2 antibodies
Rabbit
Clonality
All clonalities for Ephrin B2 antibodies
Polyclonal
Conjugate
All conjugates for Ephrin B2 antibodies
This Ephrin B2 antibody is un-conjugated
Application
All applications for Ephrin B2 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse
Purification
Affinity-chromatography using epitope-specific peptide
Immunogen
Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C.
Target Details for Ephrin B2
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Target
Ephrin B2 (EFNB2)
Alternative Name
Ephrin-B2 (EFNB2 Products )
Synonyms
EFNB2 antibody, efnb2 antibody, ephrin-B2 antibody, htkl antibody, eplg5 antibody, htk-l antibody, lerk5 antibody, ephrinB2 antibody, efnb2a antibody, MGC68890 antibody, efnb2b antibody, ELF-2 antibody, Epl5 antibody, Eplg5 antibody, Htk-L antibody, LERK-5 antibody, Lerk5 antibody, NLERK-1 antibody, EPLG5 antibody, HTKL antibody, LERK5 antibody, ephrin B2 antibody, ephrin-B2 precursor antibody, ephrin B2 L homeolog antibody, ephrin B2 S homeolog antibody, EFNB2 antibody, efnb2 antibody, efnb2.L antibody, efnb2.S antibody, Efnb2 antibody
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
Molecular Weight
37 kDa
Gene ID
1948
NCBI Accession
NP_004084
UniProt
P52799
Pathways
RTK Signaling , Regulation of Muscle Cell Differentiation
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