CXCR7 antibody (C-Term)

Catalog No. ABIN615865

Product Details anti-CXCR7 Antibody

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to G Protein-Coupled Receptor RDC1 (CXCR7).

Purification: Immunoaffinity Chromatography

Immunogen: CXCR7 antibody was raised against synthetic peptide - KLH conjugated Genename: CXCR7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Alternative Name: CXCR7 / GPR159 (CXCR7 Products)

Synonyms: CMKOR1 antibody, CXC-R7 antibody, CXCR-7 antibody, CXCR7 antibody, GPR159 antibody, RDC-1 antibody, RDC1 antibody, AW541270 antibody, Cmkor1 antibody, Cxcr7 antibody, Rdc1 antibody, ackr3 antibody, cxcr7 antibody, rdc1 antibody, xcxcr7 antibody, atypical chemokine receptor 3 antibody, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 antibody, atypical chemokine receptor 3 L homeolog antibody, ACKR3 antibody, MmrVgp88 antibody, Ackr3 antibody, ackr3.L antibody

Background: RDC1 was originally considered to be an Adrenomedullin receptor that binds calcitonin gene-related peptide (CGRP) and adrenomedullin. RDC1 and GPRN1 represent two tissue-specific subtypes of the same 60-kD receptor. RDC1 has the structural characteristics of a chemokine receptor. Recently it has been shown that RDC1 binds to the chemokine CXCL12 and should be considered to be a chemokine receptor.Synonyms: C-X-C chemokine receptor type 7, CMKOR1, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, GPR-159, RDC1

Gene ID: 57007

NCBI Accession: NP_064707

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling