CCL28 antibody

Catalog No. ABIN615627

Product Details anti-CCL28 Antibody

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL28 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Specificity: Recognizes Human MEC. Other species not tested.

Purification: Affinity Chromatography employing an immobilized Human MEC matrix.

Immunogen: Highly pure recombinant Human MEC.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Expiry Date: 6 months

Target Details for CCL28

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: MEC / CCL28 (CCL28 Products)

Synonyms: Scya28 antibody, CCL28 antibody, ccl28 antibody, nrpb antibody, enc-1 antibody, pig10 antibody, Encr-3 antibody, klhl35 antibody, Xencr-3 antibody, tp53i10 antibody, LOC100303767 antibody, CCK1 antibody, MEC antibody, SCYA28 antibody, C-C motif chemokine ligand 28 antibody, ectodermal-neural cortex 1 (with BTB domain) antibody, C-C motif chemokine 28 antibody, chemokine (C-C motif) ligand 28 antibody, Ccl28 antibody, CCL28 antibody, ccl28 antibody, enc1 antibody, LOC100303767 antibody

Background: CCL28, also known as chemokine (C-C motif) ligand 28 or mucosae-associated epithelial chemokine (MEC), belongs to the subfamily of small cytokine CC proteins. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. This chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury.Synonyms: C-C motif chemokine 28, Mucosae-associated epithelial chemokine, Protein CCK1, SCYA28, Small-inducible cytokine A28

Gene ID: 56477

NCBI Accession: NP_683513

UniProt: Q9NRJ3