MMP3 antibody (Ser373)

Catalog No. ABIN615526

Product Details anti-MMP3 Antibody

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Binding Specificity: Ser373

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Sequence: K-R-SP-F-F

Specificity: This antibody detects MMP-3.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogen: Synthesized non-phosphopeptide derived from human Myc around the phosphorylation site of serine 373

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-glycine, pH 7, 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C. Dilute only prior to immediate use.

Target Details for MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Alternative Name: MMP-3 (MMP3 Products)

Background: MMP3 is a Metallopeptidase M10A type protease. Human fibroblast stromelysin/MMP3 is a proteoglycanase with a wide range of substrate specificities. It is a secreted metalloprotease produced predominantly by connective tissue cells. MMP3 is capable of degrading proteoglycan, fibronectin, laminin, and type IV collagen. Expression has been documented in breast carcinoma, wound healing and chronic inflammatory diseases.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1

Gene ID: 4314

NCBI Accession: NP_002413

UniProt: P08254