ZFAND5 antibody (AA 40-150)
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- Target See all ZFAND5 Antibodies
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
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Binding Specificity
- AA 40-150
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZFAND5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RQQNSGRMSP MGTASGSNSP TSDSASVQRA DTSLNNCEGA AGSTSEKSRN VPVAALPVTQ QMTEMSISRE DKITTPKTEV SEPVVTQPSP SVSQPSTSQS EEKAPELPKP K
- Cross-Reactivity
- Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ZFAND5 (NP_001095890.1).
- Isotype
- IgG
- Top Product
- Discover our top product ZFAND5 Primary Antibody
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- Application Notes
- WB,1:500 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
- Alternative Name
- ZFAND5 (ZFAND5 Products)
- Synonyms
- 2310057A04Rik antibody, 5830475F03Rik antibody, AA415485 antibody, Za20d2 antibody, Zfp216 antibody, ZA20D2 antibody, ZFAND5A antibody, ZNF216 antibody, wu:fi29f06 antibody, za20d2l antibody, zgc:56057 antibody, za20d2 antibody, zfand5 antibody, zfand5-a antibody, zfand5-b antibody, zfand5a antibody, znf216 antibody, id:ibd2892 antibody, wu:fb16d02 antibody, wu:fc67h07 antibody, zgc:73363 antibody, zinc finger, AN1-type domain 5 antibody, zinc finger AN1-type containing 5 antibody, zinc finger, AN1-type domain 5b antibody, zinc finger AN1-type containing 5 L homeolog antibody, zinc finger, AN1-type domain 5a antibody, Zfand5 antibody, ZFAND5 antibody, zfand5b antibody, zfand5.L antibody, zfand5a antibody
- Background
- Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.,ZFAND5,ZA20D2,ZFAND5A,ZNF216,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,ZFAND5
- Molecular Weight
- 23 kDa
- Gene ID
- 7763
- UniProt
- O76080
- Pathways
- Platelet-derived growth Factor Receptor Signaling
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