ZEB2 antibody (AA 1050-1214)

Catalog No. ABIN6150424

Product Details anti-ZEB2 Antibody

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Binding Specificity: AA 1050-1214

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SGEKPYQCDK CGKRFSHSGS YSQHMNHRYS YCKREAEERE AAEREAREKG HLEPTELLMN RAYLQSITPQ GYSDSEERES MPRDGESEKE HEKEGEDGYG KLGRQDGDEE FEEEEEESEN KSMDTDPETI RDEEETGDHS MDDSSEDGKM ETKSDHEEDN MEDGM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1050-1214 of human ZEB2 (NP_055610.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2 (ZEB2 Products)

Background: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.,ZEB2,HSPC082,SIP-1,SIP1,SMADIP1,ZFHX1B,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,ZEB2

Molecular Weight: 133 kDa/136 kDa

Gene ID: 9839

UniProt: O60315

Pathways: Tube Formation