ZEB1 antibody (AA 1-260)

Catalog No. ABIN6150422

Product Details anti-ZEB1 Antibody

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDTGKE GQEILGPEAQ ADEAGCTVKD DECESDAENE QNHDPNVEEF LQQQDTAVIF PEAPEEDQRQ GTPEASGHDE NGTPDAFSQL LTCPYCDRGY KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM TSHKSGRDQR HVTQSGCNRK FKCTECGKAF KYKHHLKEHL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZEB1 (NP_001167567.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-ZEB1 antibody (ABIN6150422)

Ju, Chen, Deng, Liu, Wang, Wang, Nie, Wang, Ding, Yao, Gui, Li, Xu, Ma, Song, Kvansakul, Zen, Zhang, Luo, Fang, Huang, Allis, Tan, Zeng, Wei, Zhao: "NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression." in: Nature communications, Vol. 8, Issue 1, pp. 928, (2018) (PubMed).

Liang, Yang, Guan, Lv, Qu, Fu, Zhao: "LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1." in: Pathology, research and practice, Vol. 214, Issue 9, pp. 1474-1481, (2018) (PubMed).

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1 (ZEB1 Products)

Synonyms: ZFH/[d]EF1 antibody, kheper antibody, zeb1 antibody, zfhx1 antibody, bzp antibody, zeb antibody, tcf8 antibody, areb6 antibody, nil2a antibody, zfhep antibody, nil-2a antibody, zfhx1a antibody, nil-2-a antibody, MGC97552 antibody, TCF8 antibody, AREB6 antibody, BZP antibody, DELTAEF1 antibody, FECD6 antibody, NIL2A antibody, PPCD3 antibody, ZFHEP antibody, ZFHX1A antibody, 3110032K11Rik antibody, MEB1 antibody, Nil2 antibody, TCF-8 antibody, Tcf18 antibody, Tcf8 antibody, Tw antibody, ZEB antibody, Zfhep antibody, Zfhx1a antibody, Zfx1a antibody, Zfx1ha antibody, [delta]EF1 antibody, deltaEF1 antibody, deltaef1 antibody, fecd6 antibody, zinc finger E-box binding homeobox 1b antibody, zinc finger E-box binding homeobox 1 antibody, zinc finger E-box binding homeobox 1 S homeolog antibody, zeb1b antibody, zeb1 antibody, ZEB1 antibody, Zeb1 antibody, zeb1.S antibody

Background: This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.,ZEB1,AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,ZEB1

Molecular Weight: 116 kDa/122 kDa/124 kDa

Gene ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation