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XRCC5 antibody (AA 540-732)
XRCC5
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-XRCC5 Antibody
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Target
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XRCC5
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Binding Specificity
All epitopes for XRCC5 antibodies
AA 540-732
Reactivity
All reactivities for XRCC5 antibodies
Human
Host
All hosts for XRCC5 antibodies
Rabbit
Clonality
All clonalities for XRCC5 antibodies
Polyclonal
Conjugate
All conjugates for XRCC5 antibodies
This XRCC5 antibody is un-conjugated
Application
All applications for XRCC5 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
IEAKKKDQVT AQEIFQDNHE DGPTAKKLKT EQGGAHFSVS SLAEGSVTSV GSVNPAENFR VLVKQKKASF EEASNQLINH IEQFLDTNET PYFMKSIDCI RAFREEAIKF SEEQRFNNFL KALQEKVEIK QLNHFWEIVV QDGITLITKE EASGSSVTAE EAKKFLAPKD KPSGDTAAVF EEGGDVDDLL DMI
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 540-732 of human Ku80 (NP_066964.1).
Isotype
IgG
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Discover our top product XRCC5 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for XRCC5
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Target
XRCC5
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Alternative Name
XRCC5 (XRCC5 Products )
Synonyms
AI314015 antibody, Ku80 antibody, Ku86 antibody, Kup80 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, NFIV antibody, xrcc5-a antibody, XRCC5 antibody, X-ray repair cross complementing 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog antibody, XRCC5 antibody, Xrcc5 antibody, xrcc5.L antibody
Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.,XRCC5,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,XRCC5
Molecular Weight
82 kDa
Gene ID
7520
UniProt
P13010
Pathways
DNA Damage Repair
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