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UVRAG antibody (AA 501-699)

UVRAG Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6150044
  • Target See all UVRAG Antibodies
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Binding Specificity
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-699
    Reactivity
    • 64
    • 37
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 60
    • 4
    Rabbit
    Clonality
    • 62
    • 2
    Polyclonal
    Conjugate
    • 25
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UVRAG antibody is un-conjugated
    Application
    • 58
    • 24
    • 13
    • 13
    • 12
    • 12
    • 9
    • 8
    • 6
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KGHRKRASSE NERLQYKTPP PSYNSALAQP VTTVPSMGET ERKITSLSSS LDTSLDFSKE NKKKGEDLVG SLNGGHANVH PSQEQGEALS GHRATVNGTL LPSEQAGSAS VQLPGEFHPV SEAELCCTVE QAEEIIGLEA TGFASGDQLE AFNCIPVDSA VAVECDEQVL GEFEEFSRRI YALNENVSSF RRPRRSSDK
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

  • Target
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Alternative Name
    UVRAG (UVRAG Products)
    Background
    This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.,UVRAG,DHTX,VPS38,p63,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Autophagy,Cardiovascular,Heart,Regulators,UVRAG
    Molecular Weight
    35 kDa/78 kDa
    Gene ID
    7405
    UniProt
    Q9P2Y5
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