Urm1 antibody (AA 1-63)

Catalog No. ABIN6149975

Product Details anti-Urm1 Antibody

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Binding Specificity: AA 1-63

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Urm1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human URM1 (NP_001252511.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Urm1

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Alternative Name: URM1 (Urm1 Products)

Synonyms: RGD1306599 antibody, C9orf74 antibody, 2900073H19Rik antibody, ubiquitin related modifier 1 antibody, ubiquitin related modifier antibody, ubiquitin-related modifier antibody, Ubiquitin-related modifier 1 homolog antibody, Urm1 antibody, LOC733109 antibody, URM1 antibody

Background: Acts as a sulfur carrier required for 2-thiolation of mcm(5S(2U at tRNA wobble positions of cytosolic tRNA(Lys, tRNA(Glu and tRNA(Gln. Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5S(2U. Also acts as a ubiquitin-like protein (UBL that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.,URM1,C9orf74,URM1

Molecular Weight: 7 kDa/11 kDa/15 kDa

Gene ID: 81605

UniProt: Q9BTM9