UQCRB antibody (AA 1-111)

Catalog No. ABIN6149960

Product Details anti-UQCRB Antibody

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Binding Specificity: AA 1-111

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UQCRB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAGKQAVSAS GKWLDGIRKW YYNAAGFNKL GLMRDDTIYE DEDVKEAIRR LPENLYNDRM FRIKRALDLN LKHQILPKEQ WTKYEEENFY LEPYLKEVIR ERKEREEWAK K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human UQCRB (NP_006285.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UQCRB

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Alternative Name: UQCRB (UQCRB Products)

Background: This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.,UQCRB,MC3DN3,QCR7,QP-C,QPC,UQBC,UQBP,UQCR6,UQPC,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Lipid Metabolism,Cytochromes,Lipases,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,UQCRB

Molecular Weight: 13 kDa/16 kDa

Gene ID: 7381

UniProt: P14927