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UNC13D antibody (AA 891-1090)

UNC13D Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149931
  • Target See all UNC13D Antibodies
    UNC13D (Unc-13 Homolog D (UNC13D))
    Binding Specificity
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 891-1090
    Reactivity
    • 23
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    • 3
    • 2
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 20
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    Application
    • 19
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    LIRKYFCSRI QQQAETTSEE LGAVTVKASY RASEQKLRVE LLSASSLLPL DSNGSSDPFV QLTLEPRHEF PELAARETQK HKKDLHPLFD ETFEFLVPAE PCRKAGACLL LTVLDYDTLG ADDLEGEAFL PLREVPGLSG SEEPGEVPQT RLPLTYPAPN GDPILQLLEG RKGDREAQVF VRLRRHRAKQ ASQHALRPAP
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 891-1090 of human UNC13D (NP_954712.1).
    Isotype
    IgG
    Top Product
    Discover our top product UNC13D Primary Antibody
  • Application Notes
    WB,1:1000 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    UNC13D (Unc-13 Homolog D (UNC13D))
    Alternative Name
    UNC13D (UNC13D Products)
    Synonyms
    FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
    Background
    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.,UNC13D,FHL3,HLH3,HPLH3,Munc13-4,Immunology & Inflammation,UNC13D
    Molecular Weight
    41 kDa/123 kDa/128 kDa
    Gene ID
    201294
    UniProt
    Q70J99
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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