UIMC1 antibody (AA 1-230)

Catalog No. ABIN6149915

Product Details anti-UIMC1 Antibody

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Binding Specificity: AA 1-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UIMC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MPRRKKKVKE VSESRNLEKK DVETTSSVSV KRKRRLEDAF IVISDSDGEE PKEENGLQKT KTKQSNRAKC LAKRKIAQMT EEEQFALALK MSEQEAREVN SQEEEEEELL RKAIAESLNS CRPSDASATR SRPLATGPSS QSHQEKTTDS GLTEGIWQLV PPSLFKGSHI SQGNEAEERE EPWDHTEKTE EEPVSGSSGS WDQSSQPVFE NVNVKSFDRC TGHSAEHTQC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UIMC1 (NP_057374.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UIMC1

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Alternative Name: UIMC1 (UIMC1 Products)

Synonyms: UIMC1 antibody, RAP80 antibody, X2HRIP110 antibody, 9430016E08Rik antibody, D330018D10Rik antibody, D630032M02Rik antibody, RIP110 antibody, Rxrip110 antibody, RGD1307009 antibody, ubiquitin interaction motif containing 1 antibody, UIMC1 antibody, Uimc1 antibody

Background: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.,UIMC1,RAP80,X2HRIP110,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Ubiquitin,UIMC1

Molecular Weight: 17 kDa/38 kDa/61 kDa/70 kDa/79 kDa

Gene ID: 51720

UniProt: Q96RL1

Pathways: DNA Damage Repair, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus