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PPP4C antibody (C-Term)
PPP4C
Reactivity: Human, Rat, Cow, Dog
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-PPP4C Antibody
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Target
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PPP4C
(Protein Phosphatase 4, Catalytic Subunit (PPP4C))
Binding Specificity
All epitopes for PPP4C antibodies
C-Term
Reactivity
All reactivities for PPP4C antibodies
Human, Rat, Cow, Dog
Host
All hosts for PPP4C antibodies
Goat
Clonality
All clonalities for PPP4C antibodies
Polyclonal
Conjugate
All conjugates for PPP4C antibodies
This PPP4C antibody is un-conjugated
Application
All applications for PPP4C antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
C-PQETRGIPSK KP
Specificity
This antibody detects PPP4C.
Cross-Reactivity (Details)
Species reactivity (expected):Cow, Dog, Rat. Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogen
Peptide from the C-term of the protein sequence according to NP_002711.1 Genename: PPP4C
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Discover our top product PPP4C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline buffer, pH 7.3 containing 0.02 % sodium azide as preservative and 0.5 % bovine serum albumin as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PPP4C
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Target
PPP4C
(Protein Phosphatase 4, Catalytic Subunit (PPP4C))
Alternative Name
PPP4C (PPP4C Products )
Synonyms
pp4 antibody, ppx antibody, pp4c antibody, pph3 antibody, MGC75928 antibody, PP4C-A antibody, gc:56413 antibody, ppp4c antibody, wu:fd05e08 antibody, zgc:56413 antibody, PP4 antibody, PP4C antibody, PPH3 antibody, PPP4 antibody, PPX antibody, 1110002D08Rik antibody, AU016079 antibody, Ppx antibody, protein phosphatase 4 catalytic subunit antibody, protein phosphatase 4, catalytic subunit a antibody, protein phosphatase 4, catalytic subunit antibody, protein phosphatase 4 catalytic subunit S homeolog antibody, ppp4c antibody, ppp4ca antibody, PPP4C antibody, Ppp4c antibody, ppp4c.S antibody
Background
Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis.Synonyms: PP-X, PP4C, PPP4, PPX, Protein phosphatase X, Serine/threonine-protein phosphatase 4 catalytic subunit
Gene ID
5531
NCBI Accession
NP_002711
UniProt
P60510
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