TWIST1 antibody (AA 103-202)

Catalog No. ABIN6149715

Product Details anti-TWIST1 Antibody

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Binding Specificity: AA 103-202

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWIST1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Sequence: YEELQTQRVM ANVRERQRTQ SLNEAFAALR KIIPTLPSDK LSKIQTLKLA ARYIDFLYQV LQSDELDSKM ASCSYVAHER LSYAFSVWRM EGAWSMSASH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 103-202 of human Twist (NP_000465.1).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TWIST1 antibody (ABIN6149715)

Ju, Chen, Deng, Liu, Wang, Wang, Nie, Wang, Ding, Yao, Gui, Li, Xu, Ma, Song, Kvansakul, Zen, Zhang, Luo, Fang, Huang, Allis, Tan, Zeng, Wei, Zhao: "NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression." in: Nature communications, Vol. 8, Issue 1, pp. 928, (2018) (PubMed).

Du, Fang, Chen, Teng, Xiao, Xie, Jin, Wang: "Effect of silencing the T‑Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6050-6058, (2018) (PubMed).

Target Details for TWIST1

Target: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Alternative Name: TWIST1 (TWIST1 Products)

Background: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.,TWIST1,ACS3,BPES2,BPES3,CRS,CRS1,CSO,SCS,TWIST,bHLHa38,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Neuron marker,TWIST1

Molecular Weight: 20 kDa

Gene ID: 7291

UniProt: Q15672

Pathways: p53 Signaling, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity