TRIM24 antibody (AA 600-820)

Catalog No. ABIN6149510

Product Details anti-TRIM24 Antibody

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Binding Specificity: AA 600-820

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DGKAFGSPMI DLSSPVGGSY NLPSLPDIDC SSTIMLDNIV RKDTNIDHGQ PRPPSNRTVQ SPNSSVPSPG LAGPVTMTSV HPPIRSPSAS SVGSRGSSGS SSKPAGADST HKVPVVMLEP IRIKQENSGP PENYDFPVVI VKQESDEESR PQNANYPRSI LTSLLLNSSQ SSTSEETVLR SDAPDSTGDQ PGLHQDNSSN GKSEWLDPSQ KSPLHVGETR K

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-820 of human TRIM24 (NP_056989.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TRIM24 (TRIM24 Products)

Background: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TRIM24,PTC6,RNF82,TF1A,TIF1,TIF1A,TIF1ALPHA,hTIF1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,MAPK-Erk Signaling Pathway,TRIM24

Molecular Weight: 113 kDa/116 kDa

Gene ID: 8805

UniProt: O15164