TRIAP1 antibody (AA 1-76)

Catalog No. ABIN6149492

Product Details anti-TRIAP1 Antibody

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Binding Specificity: AA 1-76

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MNSVGEACTD MKREYDQCFN RWFAEKFLKG DSSGDPCTDL FKRYQQCVQK AIKEKEIPIE GLEFMGHGKE KPENSS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Alternative Name: TRIAP1 (TRIAP1 Products)

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA between liposomes (in vitro and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.,TRIAP1,HSPC132,MDM35,P53CSV,WF-1,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,TRIAP1

Molecular Weight: 8 kDa

Gene ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling