NFKBIL2 antibody (AA 160-390)

Catalog No. ABIN6149388

Product Details anti-NFKBIL2 Antibody

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Binding Specificity: AA 160-390

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFKBIL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MRTRLYLNLG LTFESLQQTA LCNDYFRKSI FLAEQNHLYE DLFRARYNLG TIHWRAGQHS QAMRCLEGAR ECAHTMRKRF MESECCVVIA QVLQDLGDFL AAKRALKKAY RLGSQKPVQR AAICQNLQHV LAVVRLQQQL EEAEGRDPQG AMVICEQLGD LFSKAGDFPR AAEAYQKQLR FAELLDRPGA ERAIIHVSLA TTLGDMKDHH GAVRHYEEEL RLRSGNVLEE A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-390 of human TONSL (NP_038460.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NFKBIL2

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Alternative Name: TONSL (NFKBIL2 Products)

Background: The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.,TONSL,IKBR,NFKBIL2,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Signal Transduction,TONSL

Molecular Weight: 150 kDa

Gene ID: 4796

UniProt: Q96HA7

Pathways: Maintenance of Protein Location