TNNI3 antibody (AA 1-210)
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- Target See all TNNI3 Antibodies
- TNNI3 (Cardiac Troponin I (TNNI3))
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Binding Specificity
- AA 1-210
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNNI3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- MADGSSDAAR EPRPAPAPIR RRSSNYRAYA TEPHAKKKSK ISASRKLQLK TLLLQIAKQE LEREAEERRG EKGRALSTRC QPLELAGLGF AELQDLCRQL HARVDKVDEE RYDIEAKVTK NITEIADLTQ KIFDLRGKFK RPTLRRVRIS ADAMMQALLG ARAKESLDLR AHLKQVKKED TEKENREVGD WRKNIDALSG MEGRKKKFES
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TNNI3 (NP_000354.4).
- Isotype
- IgG
- Top Product
- Discover our top product TNNI3 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TNNI3 (Cardiac Troponin I (TNNI3))
- Alternative Name
- TNNI3 (TNNI3 Products)
- Background
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).,TNNI3,CMD1FF,CMD2A,CMH7,RCM1,TNNC1,cTnI,troponin I3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Cardiovascular,Cardiovascular Markers,Cardiomyocytes,Angiogenesis,Heart,Contractility,TNNI3
- Molecular Weight
- 24 kDa
- Gene ID
- 7137
- UniProt
- P19429
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