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TNNI3 antibody (AA 1-210)
TNNI3
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNNI3 Antibody
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Target
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TNNI3
(Cardiac Troponin I (TNNI3))
Binding Specificity
All epitopes for TNNI3 antibodies
AA 1-210
Reactivity
All reactivities for TNNI3 antibodies
Human
Host
All hosts for TNNI3 antibodies
Rabbit
Clonality
All clonalities for TNNI3 antibodies
Polyclonal
Conjugate
All conjugates for TNNI3 antibodies
This TNNI3 antibody is un-conjugated
Application
All applications for TNNI3 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Sequence
MADGSSDAAR EPRPAPAPIR RRSSNYRAYA TEPHAKKKSK ISASRKLQLK TLLLQIAKQE LEREAEERRG EKGRALSTRC QPLELAGLGF AELQDLCRQL HARVDKVDEE RYDIEAKVTK NITEIADLTQ KIFDLRGKFK RPTLRRVRIS ADAMMQALLG ARAKESLDLR AHLKQVKKED TEKENREVGD WRKNIDALSG MEGRKKKFES
Cross-Reactivity
Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TNNI3 (NP_000354.4).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TNNI3
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Target
TNNI3
(Cardiac Troponin I (TNNI3))
Alternative Name
TNNI3 (TNNI3 Products )
Synonyms
CMD1FF antibody, CMD2A antibody, CMH7 antibody, RCM1 antibody, TNNC1 antibody, cTnI antibody, CMD1Z antibody, CMH13 antibody, TN-C antibody, TNC antibody, TNNC antibody, Tn1 antibody, TnIc antibody, ctnIc antibody, XTnIc antibody, c-troponin antibody, cTNT antibody, cmh7 antibody, ctni antibody, tnnc1 antibody, TNNI3 antibody, TnI antibody, cTNI antibody, AI874626 antibody, TnC antibody, cTnC antibody, tncc antibody, Tncc antibody, troponin I3, cardiac type antibody, troponin C1, slow skeletal and cardiac type antibody, troponin I, cardiac 3 antibody, troponin I type 3 (cardiac) antibody, troponin I3, cardiac type S homeolog antibody, troponin I3, cardiac type L homeolog antibody, cardiac troponin I antibody, troponin C, cardiac/slow skeletal antibody, TNNI3 antibody, TNNC1 antibody, Tnni3 antibody, tnni3.S antibody, tnni3.L antibody, tnni3 antibody, LOC100462680 antibody, Tnnc1 antibody
Background
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).,TNNI3,CMD1FF,CMD2A,CMH7,RCM1,TNNC1,cTnI,troponin I3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Cardiovascular,Cardiovascular Markers,Cardiomyocytes,Angiogenesis,Heart,Contractility,TNNI3
Molecular Weight
24 kDa
Gene ID
7137
UniProt
P19429
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