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TLR4 antibody (AA 500-600)

TLR4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149223
  • Target See all TLR4 Antibodies
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Binding Specificity
    • 16
    • 16
    • 16
    • 16
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-600
    Reactivity
    • 178
    • 90
    • 72
    • 37
    • 23
    • 20
    • 19
    • 19
    • 5
    • 2
    • 1
    • 1
    Human
    Host
    • 129
    • 71
    • 9
    • 4
    Rabbit
    Clonality
    • 133
    • 80
    Polyclonal
    Conjugate
    • 90
    • 20
    • 20
    • 16
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is un-conjugated
    Application
    • 147
    • 129
    • 50
    • 45
    • 32
    • 28
    • 27
    • 26
    • 26
    • 24
    • 14
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    FLDLSQCQLE QLSPTAFNSL SSLQVLNMSH NNFFSLDTFP YKCLNSLQVL DYSLNHIMTS KKQELQHFPS SLAFLNLTQN DFACTCEHQS FLQWIKDQRQ L
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TLR4 (NP_612564.1).
    Isotype
    IgG
    Top Product
    Discover our top product TLR4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).

  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Alternative Name
    TLR4 (TLR4 Products)
    Synonyms
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    Background
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.,TLR4,ARMD10,CD284,TLR-4,TOLL,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TLR4
    Molecular Weight
    73 kDa/91 kDa/95 kDa
    Gene ID
    7099
    UniProt
    O00206
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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