TLE1 antibody (AA 501-770)
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- Target See all TLE1 Antibodies
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
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Binding Specificity
- AA 501-770
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TLE1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TGGKGCVKVW DISHPGNKSP VSQLDCLNRD NYIRSCKLLP DGCTLIVGGE ASTLSIWDLA APTPRIKAEL TSSAPACYAL AISPDSKVCF SCCSDGNIAV WDLHNQTLVR QFQGHTDGAS CIDISNDGTK LWTGGLDNTV RSWDLREGRQ LQQHDFTSQI FSLGYCPTGE WLAVGMESSN VEVLHVNKPD KYQLHLHESC VLSLKFAYCG KWFVSTGKDN LLNAWRTPYG ASIFQSKESS SVLSCDISVD DKYIVTGSGD KKATVYEVIY
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 501-770 of human TLE1 (NP_005068.2).
- Isotype
- IgG
- Top Product
- Discover our top product TLE1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
- Alternative Name
- TLE1 (TLE1 Products)
- Synonyms
- ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody
- Background
- Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,TLE1,ESG,ESG1,GRG1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Stem Cells,TLE1
- Molecular Weight
- 83 kDa
- Gene ID
- 7088
- UniProt
- Q04724
- Pathways
- WNT Signaling, SARS-CoV-2 Protein Interactome
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