TIA1 antibody (C-Term)
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- Target See all TIA1 Antibodies
- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TIA1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- IGYPQPYGQW GQWYGNAQQI GQYMPNGWQV PAYGMYGQAW NQQGFNQTQS SAPWMGPNYG VQPPQGQNGS MLPNQPSGYR VAGYETQ
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TIA1 (NP_071505.2).
- Isotype
- IgG
- Top Product
- Discover our top product TIA1 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
- Alternative Name
- TIA1 (TIA1 Products)
- Background
- The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.,TIA1,TIA-1,WDM,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,TIA1
- Molecular Weight
- 24 kDa/41 kDa/42 kDa
- Gene ID
- 7072
- UniProt
- P31483
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