Tescalcin antibody (AA 135-214)
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- Target See all Tescalcin (TESC) Antibodies
- Tescalcin (TESC)
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Binding Specificity
- AA 135-214
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Tescalcin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME PDQVYEGITF EDFLKIWQGI DIETKMHVRF LNMETMALCH
- Cross-Reactivity
- Human
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 135-214 of human TESC (NP_060369.3).
- Isotype
- IgG
- Top Product
- Discover our top product TESC Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Tescalcin (TESC)
- Alternative Name
- TESC (TESC Products)
- Synonyms
- TSC antibody, chp3 antibody, CHP3 antibody, 1010001A17Rik antibody, 2410011K10Rik antibody, TE-1 antibody, RGD1566317 antibody, tescalcin antibody, tescalcin L homeolog antibody, tesc antibody, TESC antibody, Tesc antibody, tesc.L antibody
- Background
- Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+/H(+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.,TESC,CHP3,TSC,tescalcin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Calcium Signaling,TESC
- Molecular Weight
- 18 kDa/21 kDa/24 kDa
- Gene ID
- 54997
- UniProt
- Q96BS2
- Pathways
- Proton Transport
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